CB(1) Allosteric Modulator Org27569 Is an Antagonist/Inverse Agonist of ERK1/2 Signaling

Introduction: Allosteric modulation of cannabinoid type-1 receptors (CB(1)) is a novel means through which signaling bias may be exerted. Org27569 remains the most-characterized CB(1) allosteric modulator, yet there are conflicting reports regarding its effects on extracellular signal-regulated kina...

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Detalles Bibliográficos
Autores principales: Gamage, Thomas F., Anderson, Johnathon C., Abood, Mary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484173/
https://www.ncbi.nlm.nih.gov/pubmed/28660254
http://dx.doi.org/10.1089/can.2016.0028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484173/
https://www.ncbi.nlm.nih.gov/pubmed/28660254
http://dx.doi.org/10.1089/can.2016.0028

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