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Anti-therapeutic antibodies and their clinical impact in patients treated with the TNF antagonist adalimumab
Patients treated with the TNF antagonist adalimumab develop anti-therapeutic antibodies (ATA), the prevalence of which varies depending on the assay used. Most assays are compromised due to the presence of adalimumab in the clinical samples. Our objective was to develop an antibody assay, applicable...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484178/ https://www.ncbi.nlm.nih.gov/pubmed/28279855 http://dx.doi.org/10.1016/j.cyto.2017.02.015 |