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Increased Amyloid Precursor Protein and Tau Expression Manifests as Key Secondary Cell Death in Chronic Traumatic Brain Injury

In testing the hypothesis of Alzheimer's disease (AD)‐like pathology in late stage traumatic brain injury (TBI), we evaluated AD pathological markers in late stage TBI model. Sprague–Dawley male rats were subjected to moderate controlled cortical impact (CCI) injury, and 6 months later euthaniz...

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Detalles Bibliográficos
Autores principales: Acosta, Sandra A., Tajiri, Naoki, Sanberg, Paul R., Kaneko, Yuji, Borlongan, Cesar V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484295/
https://www.ncbi.nlm.nih.gov/pubmed/27699791
http://dx.doi.org/10.1002/jcp.25629