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Limitations of the hCMEC/D3 cell line as a model for Aβ clearance by the human blood‐brain barrier
Alzheimer's disease and cerebral amyloid angiopathy are characterized by accumulation of amyloid‐β (Aβ) at the cerebrovasculature due to decreased clearance at the blood‐brain barrier (BBB). However, the exact mechanism of Aβ clearance across this barrier has not been fully elucidated. The hCME...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484315/ https://www.ncbi.nlm.nih.gov/pubmed/27726164 http://dx.doi.org/10.1002/jnr.23964 |