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In vitro and in vivo effects of kisspeptin antagonists p234, p271, p354, and p356 on GPR54 activation

Kisspeptins (KPs) and their receptor (GPR54 or KiSS1R) play a key-role in regulation of the hypothalamic-pituitary-gonadal axis and are therefore interesting targets for therapeutic interventions in the field of reproductive endocrinology. As dogs show a rapid and robust LH response after the admini...

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Detalles Bibliográficos
Autores principales: Albers-Wolthers, C. H. J., de Gier, J., Walen, M., van Kooten, P. J. S., Lambalk, C. B., Leegwater, P. A. J., Roelen, B. A. J., Schaefers-Okkens, A. C., Rutten, V. P. M. G., Millar, R. P. M., Kooistra, H. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484485/
https://www.ncbi.nlm.nih.gov/pubmed/28650956
http://dx.doi.org/10.1371/journal.pone.0179156