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p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate

Cleft palate is a common congenital disorder that affects up to 1 in 2500 live births and results in considerable morbidity to affected individuals and their families. The aetiology of cleft palate is complex with both genetic and environmental factors implicated. Mutations in the transcription fact...

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Detalles Bibliográficos
Autores principales: Richardson, Rose, Mitchell, Karen, Hammond, Nigel L., Mollo, Maria Rosaria, Kouwenhoven, Evelyn N., Wyatt, Niki D., Donaldson, Ian J., Zeef, Leo, Burgis, Tim, Blance, Rognvald, van Heeringen, Simon J., Stunnenberg, Hendrik G., Zhou, Huiqing, Missero, Caterina, Romano, Rose Anne, Sinha, Satrajit, Dixon, Michael J., Dixon, Jill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484519/
https://www.ncbi.nlm.nih.gov/pubmed/28604778
http://dx.doi.org/10.1371/journal.pgen.1006828