Genome-wide transposon mutagenesis of Proteus mirabilis: Essential genes, fitness factors for catheter-associated urinary tract infection, and the impact of polymicrobial infection on fitness requirements

The Gram-negative bacterium Proteus mirabilis is a leading cause of catheter-associated urinary tract infections (CAUTIs), which are often polymicrobial. Numerous prior studies have uncovered virulence factors for P. mirabilis pathogenicity in a murine model of ascending UTI, but little is known con...

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Detalles Bibliográficos
Autores principales: Armbruster, Chelsie E., Forsyth-DeOrnellas, Valerie, Johnson, Alexandra O., Smith, Sara N., Zhao, Lili, Wu, Weisheng, Mobley, Harry L. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484520/
https://www.ncbi.nlm.nih.gov/pubmed/28614382
http://dx.doi.org/10.1371/journal.ppat.1006434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484520/
https://www.ncbi.nlm.nih.gov/pubmed/28614382
http://dx.doi.org/10.1371/journal.ppat.1006434

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