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Iron elevation and adipose tissue remodeling in the epididymal depot of a mouse model of polygenic obesity

BACKGROUND: Iron dysregulation is a potential contributor to the pathology of obesity-related metabolic complications. KK/HIJ (KK) mice, a polygenic obese mouse model, have elevated serum iron levels. A subset of KK male mice display a bronzing of epididymal adipose tissue (eAT) associated with >...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoya, Pham, Vinh T., Mori, Hiroyuki, MacDougald, Ormond A., Shah, Yatrik M., Bodary, Peter F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484604/
https://www.ncbi.nlm.nih.gov/pubmed/28651003
http://dx.doi.org/10.1371/journal.pone.0179889