LARP1 functions as a molecular switch for mTORC1-mediated translation of an essential class of mRNAs

The RNA binding protein, LARP1, has been proposed to function downstream of mTORC1 to regulate the translation of 5’TOP mRNAs such as those encoding ribosome proteins (RP). However, the roles of LARP1 in the translation of 5’TOP mRNAs are controversial and its regulatory roles in mTORC1-mediated tra...

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Detalles Bibliográficos
Autores principales: Hong, Sungki, Freeberg, Mallory A, Han, Ting, Kamath, Avani, Yao, Yao, Fukuda, Tomoko, Suzuki, Tsukasa, Kim, John K, Inoki, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484620/
https://www.ncbi.nlm.nih.gov/pubmed/28650797
http://dx.doi.org/10.7554/eLife.25237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484620/
https://www.ncbi.nlm.nih.gov/pubmed/28650797
http://dx.doi.org/10.7554/eLife.25237

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