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Longitudinal imaging of Caenorhabditis elegans in a microfabricated device reveals variation in behavioral decline during aging

The roundworm C. elegans is a mainstay of aging research due to its short lifespan and easily manipulable genetics. Current, widely used methods for long-term measurement of C. elegans are limited by low throughput and the difficulty of performing longitudinal monitoring of aging phenotypes. Here we...

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Detalles Bibliográficos
Autores principales: Churgin, Matthew A, Jung, Sang-Kyu, Yu, Chih-Chieh, Chen, Xiangmei, Raizen, David M, Fang-Yen, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484621/
https://www.ncbi.nlm.nih.gov/pubmed/28537553
http://dx.doi.org/10.7554/eLife.26652