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Two-step synthesis of chiral fused tricyclic scaffolds from phenols via desymmetrization on nickel
Tricyclic furan derivatives with multiple chiral centers are ubiquitous in natural products. Construction of such tricyclic scaffolds in a stereocontrolled, step-economic, and atom-economic manner is a key challenge. Here we show a nickel-catalyzed highly enantioselective synthesis of hydronaphtho[1...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484674/ https://www.ncbi.nlm.nih.gov/pubmed/28652575 http://dx.doi.org/10.1038/s41467-017-00068-8 |