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Two-step synthesis of chiral fused tricyclic scaffolds from phenols via desymmetrization on nickel

Tricyclic furan derivatives with multiple chiral centers are ubiquitous in natural products. Construction of such tricyclic scaffolds in a stereocontrolled, step-economic, and atom-economic manner is a key challenge. Here we show a nickel-catalyzed highly enantioselective synthesis of hydronaphtho[1...

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Detalles Bibliográficos
Autores principales:	Kumar, Ravindra, Hoshimoto, Yoichi, Tamai, Eri, Ohashi, Masato, Ogoshi, Sensuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484674/ https://www.ncbi.nlm.nih.gov/pubmed/28652575 http://dx.doi.org/10.1038/s41467-017-00068-8

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