Skeletal Dysplasia Mutations Effect on Human Filamins’ Structure and Mechanosensing

Cells’ ability to sense mechanical cues in their environment is crucial for fundamental cellular processes, leading defects in mechanosensing to be linked to many diseases. The actin cross-linking protein Filamin has an important role in the conversion of mechanical forces into biochemical signals....

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Detalles Bibliográficos
Autores principales: Seppälä, Jonne, Bernardi, Rafael C., Haataja, Tatu J. K., Hellman, Maarit, Pentikäinen, Olli T., Schulten, Klaus, Permi, Perttu, Ylänne, Jari, Pentikäinen, Ulla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484675/
https://www.ncbi.nlm.nih.gov/pubmed/28652603
http://dx.doi.org/10.1038/s41598-017-04441-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484675/
https://www.ncbi.nlm.nih.gov/pubmed/28652603
http://dx.doi.org/10.1038/s41598-017-04441-x

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