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Identification of Jak-STAT signaling involvement in sarcoidosis severity via a novel microRNA-regulated peripheral blood mononuclear cell gene signature

Sarcoidosis is a granulomatous lung disorder of unknown cause. The majority of individuals with sarcoidosis spontaneously achieve full remission (uncomplicated sarcoidosis), however, ~20% of sarcoidosis-affected individuals experience progressive lung disease or cardiac and nervous system involvemen...

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Detalles Bibliográficos
Autores principales: Zhou, Tong, Casanova, Nancy, Pouladi, Nima, Wang, Ting, Lussier, Yves, Knox, Kenneth S., Garcia, Joe G. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484682/
https://www.ncbi.nlm.nih.gov/pubmed/28652588
http://dx.doi.org/10.1038/s41598-017-04109-6