Immunization with the Malaria Diversity-Covering Blood-Stage Vaccine Candidate Plasmodium falciparum Apical Membrane Antigen 1 DiCo in Complex with Its Natural Ligand PfRon2 Does Not Improve the In Vitro Efficacy

The blood-stage malaria vaccine candidate Plasmodium falciparum apical membrane antigen 1 (PfAMA1) can induce strong parasite growth-inhibitory antibody responses in animals but has not achieved the anticipated efficacy in clinical trials. Possible explanations in humans are the insufficient potency...

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Detalles Bibliográficos
Autores principales: Spiegel, Holger, Boes, Alexander, Fendel, Rolf, Reimann, Andreas, Schillberg, Stefan, Fischer, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484772/
https://www.ncbi.nlm.nih.gov/pubmed/28702028
http://dx.doi.org/10.3389/fimmu.2017.00743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484772/
https://www.ncbi.nlm.nih.gov/pubmed/28702028
http://dx.doi.org/10.3389/fimmu.2017.00743

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