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Direct Visualization of Model Membrane Remodeling by α‐Synuclein Fibrillization

The interaction of α‐synuclein (αS) with membranes is thought to be critical in the etiology of Parkinson's disease. Besides oligomeric αS aggregates that possibly form membrane pores, the aggregation of αS into amyloid fibrils has been reported to disrupt membranes. The mechanism by which aggr...

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Detalles Bibliográficos
Autores principales: Chaudhary, Himanshu, Subramaniam, Vinod, Claessens, Mireille M. A. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485007/
https://www.ncbi.nlm.nih.gov/pubmed/28370874
http://dx.doi.org/10.1002/cphc.201700050