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Role of miR‐155 in the regulation of MMP‐16 expression in intervertebral disc degeneration

The molecular mechanisms of intervertebral disc degeneration (IDD) remain elusive. We found that miR‐155 is down‐regulated in degenerative nucleus pulposus (NP), and more severe degeneration is correlated with higher matrix metallopeptidase 16 (MMP‐16) expression. MMP‐16 also degraded matrix aggreca...

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Detalles Bibliográficos
Autores principales: Zhang, Wei‐Lin, Chen, Yu‐Fei, Meng, Hong‐Zheng, Du, Jun‐Jie, Luan, Guan‐Nan, Wang, Hai‐Qiang, Yang, Mao‐Wei, Luo, Zhuo‐Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485035/
https://www.ncbi.nlm.nih.gov/pubmed/27227700
http://dx.doi.org/10.1002/jor.23313