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Secondary phenotype analysis in ascertained family designs: application to the Leiden longevity study

The case‐control design is often used to test associations between the case‐control status and genetic variants. In addition to this primary phenotype, a number of additional traits, known as secondary phenotypes, are routinely recorded, and typically, associations between genetic factors and these...

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Detalles Bibliográficos
Autores principales: Tissier, Renaud, Tsonaka, Roula, Mooijaart, Simon P., Slagboom, Eline, Houwing‐Duistermaat, Jeanine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485037/
https://www.ncbi.nlm.nih.gov/pubmed/28303589
http://dx.doi.org/10.1002/sim.7281