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Multivalent Peptide–Nanoparticle Conjugates for Influenza‐Virus Inhibition

To inhibit binding of the influenza A virus to the host cell glycocalyx, we generate multivalent peptide–polymer nanoparticles binding with nanomolar affinity to the virus via its spike protein hemagglutinin. The chosen dendritic polyglycerol scaffolds are highly biocompatible and well suited for a...

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Detalles Bibliográficos
Autores principales: Lauster, Daniel, Glanz, Maria, Bardua, Markus, Ludwig, Kai, Hellmund, Markus, Hoffmann, Ute, Hamann, Alf, Böttcher, Christoph, Haag, Rainer, Hackenberger, Christian P. R., Herrmann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485077/
https://www.ncbi.nlm.nih.gov/pubmed/28444849
http://dx.doi.org/10.1002/anie.201702005