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Generation of human antibody fragments against Streptococcus mutans using a phage display chain shuffling approach

BACKGROUND: Common oral diseases and dental caries can be prevented effectively by passive immunization. In humans, passive immunotherapy may require the use of humanized or human antibodies to prevent adverse immune responses against murine epitopes. Therefore we generated human single chain and di...

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Detalles Bibliográficos
Autores principales: Kupper, Michael B, Huhn, Michael, Spiegel, Holger, Ma, Julian KC, Barth, Stefan, Fischer, Rainer, Finnern, Ricarda
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548521/
https://www.ncbi.nlm.nih.gov/pubmed/15667665
http://dx.doi.org/10.1186/1472-6750-5-4