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Generation of human antibody fragments against Streptococcus mutans using a phage display chain shuffling approach
BACKGROUND: Common oral diseases and dental caries can be prevented effectively by passive immunization. In humans, passive immunotherapy may require the use of humanized or human antibodies to prevent adverse immune responses against murine epitopes. Therefore we generated human single chain and di...
Autores principales: | Kupper, Michael B, Huhn, Michael, Spiegel, Holger, Ma, Julian KC, Barth, Stefan, Fischer, Rainer, Finnern, Ricarda |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548521/ https://www.ncbi.nlm.nih.gov/pubmed/15667665 http://dx.doi.org/10.1186/1472-6750-5-4 |
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