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Loss of ADAMTS5 enhances brown adipose tissue mass and promotes browning of white adipose tissue via CREB signaling

OBJECTIVE: A potential strategy to treat obesity – and the associated metabolic consequences – is to increase energy expenditure. This could be achieved by stimulating thermogenesis through activation of brown adipose tissue (BAT) and/or the induction of browning of white adipose tissue (WAT). Over...

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Detalles Bibliográficos
Autores principales: Bauters, Dries, Cobbaut, Mathias, Geys, Lotte, Van Lint, Johan, Hemmeryckx, Bianca, Lijnen, H. Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485238/
https://www.ncbi.nlm.nih.gov/pubmed/28702327
http://dx.doi.org/10.1016/j.molmet.2017.05.004