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A high-content small molecule screen identifies novel inducers of definitive endoderm

OBJECTIVES: Human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) can generate any given cell type in the human body. One challenge for cell-replacement therapy is the efficient differentiation and expansion of large quantities of progenitor cells from pluripotent stem...

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Detalles Bibliográficos
Autores principales: Korostylev, Alexander, Mahaddalkar, Pallavi U., Keminer, Oliver, Hadian, Kamyar, Schorpp, Kenji, Gribbon, Philip, Lickert, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485240/
https://www.ncbi.nlm.nih.gov/pubmed/28702321
http://dx.doi.org/10.1016/j.molmet.2017.04.009