Uncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male mice

OBJECTIVE: Upregulation of uncoupling protein 2 (UCP2) is associated with impaired glucose-stimulated insulin secretion (GSIS), which is thought to be an important contributor to pathological β cell failure in obesity and type 2 diabetes (T2D); however, the physiological function of UCP2 in the β ce...

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Detalles Bibliográficos
Autores principales: Seshadri, Nivedita, Jonasson, Michael E., Hunt, Kristin L., Xiang, Bo, Cooper, Steven, Wheeler, Michael B., Dolinsky, Vernon W., Doucette, Christine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485245/
https://www.ncbi.nlm.nih.gov/pubmed/28702331
http://dx.doi.org/10.1016/j.molmet.2017.04.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485245/
https://www.ncbi.nlm.nih.gov/pubmed/28702331
http://dx.doi.org/10.1016/j.molmet.2017.04.008

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