Cargando…

miR-200c Accelerates Hepatic Stellate Cell-Induced Liver Fibrosis via Targeting the FOG2/PI3K Pathway

BACKGROUND: Although expression of miR-200s is aberrant in liver fibrosis, its role in liver fibrogenesis still remains unknown. Here, we investigated the role of miR-200c in the activation of human hepatic stellate cells (HSCs) and induction of liver fibrosis. METHODS: We engineered human HSCs (LX2...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Tengfei, Cai, Xiuqin, Wang, Zifeng, Huang, Li, Wang, Chang, Jiang, Songshan, Hua, Yunpeng, Liu, Quentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485280/
https://www.ncbi.nlm.nih.gov/pubmed/28691020
http://dx.doi.org/10.1155/2017/2670658