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Grandpaternal-induced transgenerational dietary reprogramming of the unfolded protein response in skeletal muscle

OBJECTIVE: Parental nutrition and lifestyle impact the metabolic phenotype of the offspring. We have reported that grandpaternal chronic high-fat diet (HFD) transgenerationally impairs glucose metabolism in subsequent generations. Here we determined whether grandpaternal diet transgenerationally imp...

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Detalles Bibliográficos
Autores principales: Alm, Petter S., de Castro Barbosa, Thais, Barrès, Romain, Krook, Anna, Zierath, Juleen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485306/
https://www.ncbi.nlm.nih.gov/pubmed/28702319
http://dx.doi.org/10.1016/j.molmet.2017.05.009