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Neonatal GLP1R activation limits adult adiposity by durably altering hypothalamic architecture

OBJECTIVE: Adult obesity risk is influenced by alterations to fetal and neonatal environments. Modifying neonatal gut or neurohormone signaling pathways can have negative metabolic consequences in adulthood. Here we characterize the effect of neonatal activation of glucagon like peptide-1 (GLP-1) re...

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Detalles Bibliográficos
Autores principales: Rozo, Andrea V., Babu, Daniella A., Suen, PoMan A., Groff, David N., Seeley, Randy J., Simmons, Rebecca A., Seale, Patrick, Ahima, Rexford S., Stoffers, Doris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485307/
https://www.ncbi.nlm.nih.gov/pubmed/28702330
http://dx.doi.org/10.1016/j.molmet.2017.05.006