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HMGB1 and Extracellular Histones Significantly Contribute to Systemic Inflammation and Multiple Organ Failure in Acute Liver Failure

Acute liver failure (ALF) is the culmination of severe liver cell injury from a variety of causes. ALF occurs when the extent of hepatocyte death exceeds the hepatic regenerative capacity. ALF has a high mortality that is associated with multiple organ failure (MOF) and sepsis; however, the underlyi...

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Detalles Bibliográficos
Autores principales: Yang, Runkuan, Zou, Xiaoping, Tenhunen, Jyrki, Tønnessen, Tor Inge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485317/
https://www.ncbi.nlm.nih.gov/pubmed/28694564
http://dx.doi.org/10.1155/2017/5928078