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Global Autorecognition and Activation of Complement by Mannan-Binding Lectin in a Mouse Model of Type 1 Diabetes

Increasing evidence links mannan-binding lectin (MBL) to late vascular complications of diabetes. MBL is a complement-activating pattern recognition molecule of the innate immune system that can mediate an inflammation response through activation of the lectin pathway. In two recent animal studies,...

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Detalles Bibliográficos
Autores principales: Axelgaard, Esben, Østergaard, Jakob Appel, Haxha, Saranda, Thiel, Steffen, Hansen, Troels Krarup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485322/
https://www.ncbi.nlm.nih.gov/pubmed/28751823
http://dx.doi.org/10.1155/2017/9403754