Cargando…

Global Autorecognition and Activation of Complement by Mannan-Binding Lectin in a Mouse Model of Type 1 Diabetes

Increasing evidence links mannan-binding lectin (MBL) to late vascular complications of diabetes. MBL is a complement-activating pattern recognition molecule of the innate immune system that can mediate an inflammation response through activation of the lectin pathway. In two recent animal studies,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Axelgaard, Esben, Østergaard, Jakob Appel, Haxha, Saranda, Thiel, Steffen, Hansen, Troels Krarup
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485322/ https://www.ncbi.nlm.nih.gov/pubmed/28751823 http://dx.doi.org/10.1155/2017/9403754

Ejemplares similares

Diabetes Is Associated with Increased Autoreactivity of Mannan-Binding Lectin
por: Axelgaard, Esben, et al.
Publicado: (2017)

Effect of Optimization of Glycaemic Control on Mannan-Binding Lectin in Type 1 Diabetes
por: Dørflinger, Gry Høst, et al.
Publicado: (2017)

Increased Autoreactivity of the Complement-Activating Molecule Mannan-Binding Lectin in a Type 1 Diabetes Model
por: Østergaard, Jakob Appel, et al.
Publicado: (2016)

Mannan-Binding Lectin in Diabetic Kidney Disease: The Impact of Mouse Genetics in a Type 1 Diabetes Model
por: Østergaard, Jakob Appel, et al.
Publicado: (2012)

Ficolin B in Diabetic Kidney Disease in a Mouse Model of Type 1 Diabetes
por: Holt, Charlotte Berg, et al.
Publicado: (2015)

Clinical manifestations of mannan-binding lectin deficiency
por: Thiel, S., et al.
Publicado: (2006)

Mannan-binding lectin and procalcitonin measurement for prediction of postoperative infection
por: Siassi, Michael, et al.
Publicado: (2005)

Complement Receptor 2 Based Immunoassay Measuring Activation of the Complement System at C3-Level in Plasma Samples From Mice and Humans
por: Halkjær, Lene, et al.
Publicado: (2020)

Correction: Mannan-binding lectin and procalcitonin measurement for prediction of postoperative infection
por: Siassi, Michael, et al.
Publicado: (2005)

Complement Receptor 1/Cd35 Is a Receptor for Mannan-Binding Lectin
por: Ghiran, Ionita, et al.
Publicado: (2000)

Mannan-Binding Lectin in Cardiovascular Disease
por: Pągowska-Klimek, Izabela, et al.
Publicado: (2014)

Applications of mannose-binding lectins and mannan glycoconjugates in nanomedicine
por: Gupta, Anita, et al.
Publicado: (2022)

Mannan-binding lectin in cerebrospinal fluid: a leptomeningeal protein
por: Reiber, Hansotto, et al.
Publicado: (2012)

Mannan binding lectin triggers mobilization of hematopoietic stem cells
por: Adamiak, Mateusz, et al.
Publicado: (2017)

Targeting of Liver Mannan-Binding Lectin–Associated Serine Protease-3 with RNA Interference Ameliorates Disease in a Mouse Model of Rheumatoid Arthritis
por: Banda, Nirmal K., et al.
Publicado: (2018)

Low Levels of Mannan-Binding Lectin or Ficolins Are Not Associated with an Increased Risk of Cytomegalovirus Disease in HIV-Infected Patients
por: Egli, Adrian, et al.
Publicado: (2013)

The Role of Mannan-Binding Lectin (MBL) Gene Polymorphism in Ulcerative Colitis
por: Wang, Fang-Yu, et al.
Publicado: (2008)

Mannan-Binding Lectin Attenuates Inflammatory Arthritis Through the Suppression of Osteoclastogenesis
por: Dong, Lijun, et al.
Publicado: (2019)

Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel
por: Zachar, Rikke, et al.
Publicado: (2022)

Mannan-binding lectin ameliorates renal fibrosis by suppressing macrophage-to-myofibroblast transition
por: Xu, Li, et al.
Publicado: (2023)

A solution structure analysis reveals a bent collagen triple helix in the complement activation recognition molecule mannan-binding lectin
por: Iqbal, Hina, et al.
Publicado: (2022)

Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation
por: Nan, Ruodan, et al.
Publicado: (2017)

The salivary scavenger and agglutinin binds MBL and regulates the lectin pathway of complement in solution and on surfaces
por: Reichhardt, Martin P., et al.
Publicado: (2012)

Mannan binding lectin as an adjunct to risk assessment for myocardial infarction in individuals with enhanced risk
por: Saevarsdottir, Saedis, et al.
Publicado: (2005)

Mannan-binding lectin regulates dendritic cell maturation and cytokine production induced by lipopolysaccharide
por: Wang, Mingyong, et al.
Publicado: (2011)

Lysyl Hydroxylase 3 Modifies Lysine Residues to Facilitate Oligomerization of Mannan-Binding Lectin
por: Risteli, Maija, et al.
Publicado: (2014)

Mannan-Binding Lectin Suppresses Peptidoglycan-Induced TLR2 Activation and Inflammatory Responses
por: Wang, Fanping, et al.
Publicado: (2019)

High normal TSH is associated with lower mannan-binding lectin in women of childbearing age
por: Karbownik-Lewinska, Malgorzata, et al.
Publicado: (2020)

A Novel Evidence That Mannan Binding Lectin (MBL) Pathway of Complement Cascade Activation is Involved in Homing and Engraftment of Hematopoietic Stem Progenitor Cells (HSPCs)
por: Adamiak, Mateusz, et al.
Publicado: (2020)

Novel evidence that the mannan-binding lectin pathway of complement activation plays a pivotal role in triggering mobilization of hematopoietic stem/progenitor cells by activation of both the complement and coagulation cascades
por: Adamiak, M, et al.
Publicado: (2017)

Association between Low Levels of Mannan-Binding Lectin and Markers of Autoimmune Thyroid Disease in Pregnancy
por: Potlukova, Eliska, et al.
Publicado: (2013)

Defective activities, but not secretions, resulting from gene point mutations of human mannan-binding lectin
por: LIU, YING, et al.
Publicado: (2012)

Mannan-Binding Lectin Is Involved in the Protection against Renal Ischemia/Reperfusion Injury by Dietary Restriction
por: Shushimita, Shushimita, et al.
Publicado: (2015)

Correction to: High normal TSH is associated with lower mannan-binding lectin in women of childbearing age
por: Karbownik-Lewinska, Malgorzata, et al.
Publicado: (2020)

Decreased mannan-binding lectin level in adults with hypopituitarism; dependence on appropriate hormone replacement therapies
por: Matusiak, Aleksandra E., et al.
Publicado: (2023)

Extensive Basal Level Activation of Complement Mannose-Binding Lectin-Associated Serine Protease-3: Kinetic Modeling of Lectin Pathway Activation Provides Possible Mechanism
por: Oroszlán, Gábor, et al.
Publicado: (2017)

Mannan-Binding Lectin Levels and Activity Are Not Altered in Atopic Dermatitis Patients with a History of Eczema Herpeticum
por: Bundy, Kemp W., et al.
Publicado: (2011)

Toll-like receptors (TLRs) and mannan-binding lectin (MBL): On constant alert in a hostile environment
por: Bergman, Ingrid-Maria
Publicado: (2011)

Possible disease-modifying factors: the mannan-binding lectin pathway and infections in hereditary angioedema of children and adults
por: Cedzyński, Maciej, et al.
Publicado: (2008)

The pattern-recognition molecule H-ficolin in relation to diabetic kidney disease, mortality, and cardiovascular events in type 1 diabetes
por: Østergaard, Jakob Appel, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ljkvc6jrpjn9cplcaftel32o05