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Expression and Function of Granzymes A and B in Escherichia coli Peritonitis and Sepsis

Escherichia (E.) coli is the most common causative pathogen in peritonitis, the second most common cause of sepsis. Granzymes (gzms) are serine proteases traditionally implicated in cytotoxicity and, more recently, in the inflammatory response. We here sought to investigate the role of gzms in the h...

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Detalles Bibliográficos
Autores principales: García-Laorden, M. Isabel, Stroo, Ingrid, Terpstra, Sanne, Florquin, Sandrine, Medema, Jan Paul, van´t Veer, Cornelis, de Vos, Alex F., van der Poll, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485334/
https://www.ncbi.nlm.nih.gov/pubmed/28694562
http://dx.doi.org/10.1155/2017/4137563