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WDR62 Regulates Early Neural and Glial Progenitor Specification of Human Pluripotent Stem Cells

Mutations in WD40-repeat protein 62 (WDR62) are commonly associated with primary microcephaly and other developmental cortical malformations. We used human pluripotent stem cells (hPSC) to examine WDR62 function during human neural differentiation and model early stages of human corticogenesis. Neur...

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Detalles Bibliográficos
Autores principales: Alshawaf, Abdullah J., Antonic, Ana, Skafidas, Efstratios, Ng, Dominic Chi-Hung, Dottori, Mirella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485354/
https://www.ncbi.nlm.nih.gov/pubmed/28690640
http://dx.doi.org/10.1155/2017/7848932