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WDR62 Regulates Early Neural and Glial Progenitor Specification of Human Pluripotent Stem Cells
Mutations in WD40-repeat protein 62 (WDR62) are commonly associated with primary microcephaly and other developmental cortical malformations. We used human pluripotent stem cells (hPSC) to examine WDR62 function during human neural differentiation and model early stages of human corticogenesis. Neur...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485354/ https://www.ncbi.nlm.nih.gov/pubmed/28690640 http://dx.doi.org/10.1155/2017/7848932 |