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Biosynthesis of Fluorinated Peptaibols Using a Site-Directed Building Block Incorporation Approach

[Image: see text] Synthetic biological approaches, such as site-directed biosynthesis, have contributed to the expansion of the chemical space of natural products, making possible the biosynthesis of unnatural metabolites that otherwise would be difficult to access. Such methods may allow the incorp...

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Detalles Bibliográficos
Autores principales: Rivera-Chávez, José, Raja, Huzefa A., Graf, Tyler N., Burdette, Joanna E., Pearce, Cedric J., Oberlies, Nicholas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485375/
https://www.ncbi.nlm.nih.gov/pubmed/28594169
http://dx.doi.org/10.1021/acs.jnatprod.7b00189