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Tailored chondroitin sulfate glycomimetics via a tunable multivalent scaffold for potentiating NGF/TrkA-induced neurogenesis

The challenges inherent in the synthesis of large glycosaminoglycan (GAG) polysaccharides have made chemically accessible multivalent glycoligands a valuable tool in the field of GAG mimetics. However, the difficulty of positioning sulfated sugar motifs at desired sites has hindered efforts to preci...

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Detalles Bibliográficos
Autores principales: Liu, Pei, Chen, Liwei, Toh, Jerry K. C., Ang, Yi Li, Jee, Joo-Eun, Lim, Jaehong, Lee, Su Seong, Lee, Song-Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485393/
https://www.ncbi.nlm.nih.gov/pubmed/28694940
http://dx.doi.org/10.1039/c4sc02553a