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PET Tracer (18)F-Fluciclovine Can Detect Histologically Proven Bone Metastatic Lesions: A Preclinical Study in Rat Osteolytic and Osteoblastic Bone Metastasis Models

(18)F-Fluciclovine (trans-1-amino-3-(18)F-fluorocyclobutanecarboxylic acid; anti-(18)F-FACBC) is a positron emission tomography (PET) tracer for diagnosing cancers (e.g., prostate and breast cancer). The most frequent metastatic organ of these cancers is bone. Fluciclovine-PET can visualize bony les...

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Detalles Bibliográficos
Autores principales: Oka, Shuntaro, Kanagawa, Masaru, Doi, Yoshihiro, Schuster, David M., Goodman, Mark M., Yoshimura, Hirokatsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485422/
https://www.ncbi.nlm.nih.gov/pubmed/28656060
http://dx.doi.org/10.7150/thno.19883