c-Myc is Required for BRAF(V600E)-Induced Epigenetic Silencing by H3K27me3 in Tumorigenesis

BRAF(V600E) mutation is frequently found in human cancers particularly thyroid cancer and melanoma, and is involved in the regulation of gene expression through activating MAPK/Erk signaling. Trimethylation of histone 3 lysine 27 (H3K27me3) is a critical epigenetic mark for the maintenance of gene s...

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Detalles Bibliográficos
Autores principales: Qu, Yiping, Yang, Qi, Liu, Juan, Shi, Bingyin, Ji, Meiju, Li, Gang, Hou, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485424/
https://www.ncbi.nlm.nih.gov/pubmed/28656062
http://dx.doi.org/10.7150/thno.19884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485424/
https://www.ncbi.nlm.nih.gov/pubmed/28656062
http://dx.doi.org/10.7150/thno.19884

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