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Organelle acidification: an ancient cellular leak detector
Intracellular membrane-bounded organelles of eukaryotic cells transiently contact the extracellular environment during endocytosis and secretion. Such contacts must be precisely timed to prevent leakage of cargo. I argue that early eukaryotes evolved organelle acidification as a way to detect and pr...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485493/ https://www.ncbi.nlm.nih.gov/pubmed/28651577 http://dx.doi.org/10.1186/s12915-017-0395-1 |