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MYC Deregulation in Primary Human Cancers

MYC regulates a complex biological program by transcriptionally activating and repressing its numerous target genes. As such, MYC is a master regulator of many processes, including cell cycle entry, ribosome biogenesis, and metabolism. In cancer, the activity of the MYC transcriptional network is fr...

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Detalles Bibliográficos
Autores principales: Kalkat, Manpreet, De Melo, Jason, Hickman, Katherine Ashley, Lourenco, Corey, Redel, Cornelia, Resetca, Diana, Tamachi, Aaliya, Tu, William B., Penn, Linda Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485515/
https://www.ncbi.nlm.nih.gov/pubmed/28587062
http://dx.doi.org/10.3390/genes8060151