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R Loops in the Regulation of Antibody Gene Diversification

For nearly three decades, R loops have been closely linked with class switch recombination (CSR), the process that generates antibody isotypes and that occurs via a complex cascade initiated by transcription-coupled mutagenesis in switch recombination sequences. R loops form during transcription of...

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Detalles Bibliográficos
Autor principal: Pavri, Rushad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485518/
https://www.ncbi.nlm.nih.gov/pubmed/28574479
http://dx.doi.org/10.3390/genes8060154