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R Loops in the Regulation of Antibody Gene Diversification
For nearly three decades, R loops have been closely linked with class switch recombination (CSR), the process that generates antibody isotypes and that occurs via a complex cascade initiated by transcription-coupled mutagenesis in switch recombination sequences. R loops form during transcription of...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485518/ https://www.ncbi.nlm.nih.gov/pubmed/28574479 http://dx.doi.org/10.3390/genes8060154 |