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The Dual Roles of MYC in Genomic Instability and Cancer Chemoresistance
Cancer is associated with genomic instability and aging. Genomic instability stimulates tumorigenesis, whereas deregulation of oncogenes accelerates DNA replication and increases genomic instability. It is therefore reasonable to assume a positive feedback loop between genomic instability and oncoge...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485522/ https://www.ncbi.nlm.nih.gov/pubmed/28590415 http://dx.doi.org/10.3390/genes8060158 |