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The Dual Roles of MYC in Genomic Instability and Cancer Chemoresistance

Cancer is associated with genomic instability and aging. Genomic instability stimulates tumorigenesis, whereas deregulation of oncogenes accelerates DNA replication and increases genomic instability. It is therefore reasonable to assume a positive feedback loop between genomic instability and oncoge...

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Detalles Bibliográficos
Autores principales: Kumari, Alpana, Folk, Watson P., Sakamuro, Daitoku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485522/
https://www.ncbi.nlm.nih.gov/pubmed/28590415
http://dx.doi.org/10.3390/genes8060158

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