A novel TRPM8 agonist relieves dry eye discomfort

BACKGROUND: Physical cooling of the eye surface relieves ocular discomfort, but translating this event to drug treatment of dry eye discomfort not been studied. Here, we synthesized a water-soluble TRPM8 receptor agonist called cryosim-3 (C3, 1-diisopropylphosphorylnonane) which selectively activate...

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Detalles Bibliográficos
Autores principales: Yang, Jee Myung, Li, Fengxian, Liu, Qin, Rüedi, Marco, Wei, Edward Tak, Lentsman, Michael, Lee, Hyo Seok, Choi, Won, Kim, Seong Jin, Yoon, Kyung Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485613/
https://www.ncbi.nlm.nih.gov/pubmed/28651550
http://dx.doi.org/10.1186/s12886-017-0495-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485613/
https://www.ncbi.nlm.nih.gov/pubmed/28651550
http://dx.doi.org/10.1186/s12886-017-0495-2

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