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MicroRNA-142-3p and let-7g Negatively Regulates Augmented IL-6 Production in Neonatal Polymorphonuclear Leukocytes

Neonatal PMN are qualitatively impaired in functions, yet they frequently reveal augmented inflammatory reactions during sepsis. Here, we hypothesized that PMN from newborns produce more IL-6 than those from adults under LPS stimulation, in which transcriptional or posttranscriptional regulation is...

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Detalles Bibliográficos
Autores principales: Huang, Hsin-Chun, Yu, Hong-Ren, Hsu, Te-Yao, Chen, I-Lun, Huang, Hui-Chen, Chang, Jen-Chieh, Yang, Kuender D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485625/
https://www.ncbi.nlm.nih.gov/pubmed/28655995
http://dx.doi.org/10.7150/ijbs.17030