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Mismatch repair deficiency screening in colorectal carcinoma by a four-antibody immunohistochemical panel in Pakistani population and its correlation with histopathological parameters

BACKGROUND: Microsatellite instability (MSI) operates as the second major pathway in the colorectal carcinogenesis. Although genetic testing remains the gold standard for the detection of MSI, the College of American Pathologists (CAP) recommends an initial immunohistochemical workup with a four-ant...

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Detalles Bibliográficos
Autores principales: Hashmi, Atif Ali, Ali, Rabia, Hussain, Zubaida Fida, Faridi, Naveen, Khan, Erum Yousuf, Bakar, Syed Muhammad Abu, Edhi, Muhammad Muzzammil, Khan, Mehmood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485685/
https://www.ncbi.nlm.nih.gov/pubmed/28651545
http://dx.doi.org/10.1186/s12957-017-1158-8