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Genomewide Association Study Identifies Novel Genetic Loci That Modify Antiplatelet Effects and Pharmacokinetics of Clopidogrel

Genetic variants in the pharmacokinetic (PK) mechanism are the main underlying factors affecting the antiplatelet response to clopidogrel. Using a genomewide association study (GWAS) to identify new genetic loci that modify antiplatelet effects in Chinese patients with coronary heart disease, we ide...

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Detalles Bibliográficos
Autores principales: Zhong, W‐P, Wu, H, Chen, J‐Y, Li, X‐X, Lin, H‐M, Zhang, B, Zhang, Z‐W, Ma, D‐L, Sun, S, Li, H‐P, Mai, L‐P, He, G‐D, Wang, X‐P, Lei, H‐P, Zhou, H‐K, Tang, L, Liu, S‐W, Zhong, S‐L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485718/
https://www.ncbi.nlm.nih.gov/pubmed/27981573
http://dx.doi.org/10.1002/cpt.589