Bifunctional Enzyme JMJD6 Contributes to Multiple Disease Pathogenesis: New Twist on the Old Story

Jumonji domain-containing protein 6 (JMJD6) is a non-heme Fe(II) 2-oxoglutarate (2OG)-dependent oxygenase with arginine demethylase and lysyl hydroxylase activities. Its initial discovery as a dispensable phosphatidylserine receptor (PSR) in the cell membrane of macrophages for phagocytosis was squa...

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Detalles Bibliográficos
Autores principales: Vangimalla, Shiva Shankar, Ganesan, Murali, Kharbanda, Kusum K., Osna, Natalia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485730/
https://www.ncbi.nlm.nih.gov/pubmed/28587176
http://dx.doi.org/10.3390/biom7020041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485730/
https://www.ncbi.nlm.nih.gov/pubmed/28587176
http://dx.doi.org/10.3390/biom7020041

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