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Design of an intelligent sub-50 nm nuclear-targeting nanotheranostic system for imaging guided intranuclear radiosensitization

Clinically applied chemotherapy and radiotherapy is sometimes not effective due to the limited dose acting on DNA chains resident in the nuclei of cancerous cells. Herein, we develop a new theranostic technique of “intranuclear radiosensitization” aimed at directly damaging the DNA within the nucleu...

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Detalles Bibliográficos
Autores principales: Fan, Wenpei, Shen, Bo, Bu, Wenbo, Zheng, Xiangpeng, He, Qianjun, Cui, Zhaowen, Zhao, Kuaile, Zhang, Shengjian, Shi, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485887/
https://www.ncbi.nlm.nih.gov/pubmed/28694946
http://dx.doi.org/10.1039/c4sc03080j