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Design of an intelligent sub-50 nm nuclear-targeting nanotheranostic system for imaging guided intranuclear radiosensitization
Clinically applied chemotherapy and radiotherapy is sometimes not effective due to the limited dose acting on DNA chains resident in the nuclei of cancerous cells. Herein, we develop a new theranostic technique of “intranuclear radiosensitization” aimed at directly damaging the DNA within the nucleu...
Autores principales: | Fan, Wenpei, Shen, Bo, Bu, Wenbo, Zheng, Xiangpeng, He, Qianjun, Cui, Zhaowen, Zhao, Kuaile, Zhang, Shengjian, Shi, Jianlin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485887/ https://www.ncbi.nlm.nih.gov/pubmed/28694946 http://dx.doi.org/10.1039/c4sc03080j |
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