Stability Profiles and Therapeutic Effect of Cu/Zn Superoxide Dismutase Chemically Coupled to O-Quaternary Chitosan Derivatives against Dextran Sodium Sulfate-Induced Colitis

Superoxide dismutase (SOD) has attracted considerable attention on treatment of reactive oxygen species (ROS)-related disorders. We previously conjugated Cu/Zn SOD to O-quaternary chitosan derivatives (O-HTCC) to yield a polymer–enzyme conjugate O-HTCC-SOD that demonstrated superior therapeutic effe...

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Detalles Bibliográficos
Autores principales: Zhao, Nan, Feng, Zhaolong, Shao, Meng, Cao, Jichao, Wang, Fengshan, Liu, Chunhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485945/
https://www.ncbi.nlm.nih.gov/pubmed/28538700
http://dx.doi.org/10.3390/ijms18061121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485945/
https://www.ncbi.nlm.nih.gov/pubmed/28538700
http://dx.doi.org/10.3390/ijms18061121

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